Abstract Paper
| Title | : Dextrin Assisted Hydroxyapatite nanopowders using Hydrothermal method for Biomedical Application |
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| Author(s) | : C. Elavarasi, K. Gopinath, V. Collins Arun Prakash* |
| Article Information | : Volume 10 - Issue 01 (June - 2026) , 1364-1370 |
| Affiliation(s) | : Department of Chemistry, Sacred Heart College (Autono mous), Tirupattur-635 601, Tamil Nadu, India. |
Abstract :
In the present work, the hydroxyapatite nanopowders were successfully synthesized by hydrothermal method using calcium nitrate tetrahydrate and diammonium hydrogen phosphate as precursor materials with addition of dextrin. Concentrations of 1% and 1.5% of dextrin were selected, and its effect on the structural, morphological and biological characteristics of HAP nanoparticles was investigated. The synthesized samples were analyzed by Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM). FTIR analysis showed the existence of characteristic functional groups of phosphate and hydroxyl of hydroxyapatite and dextrin related functional groups, thus demonstrating dextrin interaction with HAP. The XRD results showed that the phase-pure hexagonal hydroxyapatite with higher crystallinity was obtained with the increase of dextrin concentration. SEM images showed that dextrin substantially decreased the particle agglomeration and enhanced the dispersion of particles, leading to an even more homogeneous structure of the nanostructure. The cytotoxicity assays conducted on the MG-63 osteoblast-like cell lines determined a high degree of biocompatibility, with a maximum cell viability of 98.24% after 24 hours for Dx–1% at 0.5 µg/ml. The obtained results indicate that the hydroxyapatite nanopowders prepared by the addition of dextrin have superior physicochemical and biological characteristics, which makes them very appealing for biomedical applications.
| Keywords | : Hydroxyapatite, Nanoparticles, Dextrin, Hydrothermal synthesis, Biomedical applications. |
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| Document Type | : Research Paper |
| Publication date | : June 16, 2026 |